The fact that nothing; no wisdom, no insight, no plan can succeed against the LORD is proclaimed. The LORD is sovereign and controls people and nations. (16:4, 9, 19:21, 21:1) Being sovereign simply means that he exercises supreme and permanent authority. God is absolute. He has absolute right and ability to do all things according to his own good pleasure. (Daniel 4:25, 35; Romans 9:15-23; 1 Corinthians 3:19-20; 1 Timothy 6:15; Revelations 4:11)
I am humbled reading passages like this and Romans 9:15-23. I also find hope. If one leader attacks another and I am subject to the devastation of their battle I can call on the mercy of God. Perhaps he will hear me as he did the people of Ninevah during the time of Jonah and free me from death under falling walls. I can cry out to the Sovereign LORD and help his people as Rahab did during Jericho’s end. She and her family found safety in the LORD’s sovereignty when her neighbors were crushed by falling debris. Comfort exists under the wings of the Almighty. The Sovereign is not without mercy and love.